Janet Reno, the first woman to serve as U.S. attorney general and the epicenter of several political storms during the Clinton administration, her goddaughter told the Associated Press, Reno was 78.
Reno died from complications of Parkinson's disease, her goddaughter Gabrielle D'Alemberte said. D'Alemberte said Reno spent her final days at home in Miami surrounded by family and friends.
Reno, a former prosecutor, is best known for being at the center of perhaps two of the most controversial moments of Bill Clinton’s presidency: the siege at Waco, Texas, that ended with the deaths of David Koresh, the leader of the Branch Davidians, and about 80 of his followers; and the seizure of Elian Gonzalez, the 5-year-old Cuban boy taken by federal agents from his relatives in Miami and returned to his father in Cuba.  
“After Waco, Reno figured into some of the controversies and scandals that marked the Clinton administration, including Whitewater, Filegate, bungling at the FBI laboratory, Monica Lewinsky, alleged Chinese nuclear spying and questionable campaign financing in the 1996 Clinton-Gore re-election.”

Reno ran unsuccessfully for Florida governor in 2002, losing in the Democratic primary.